Intracellular
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Cone photoreceptor cells, Oligodendrocyte precursor cells, Astrocytes, Rod photoreceptor cells)
Not detected in immune cells
Cell line enhanced (WM-115)
Interacts with GNA12 and GNA13 through the RGS domain. Interacts with RHOA, PLXNB1 and PLXNB2. Interacts with SLC1A6 (By similarity). Interacts (via DH domain) with GCSAM (via C-terminus).
GTPase activation, Guanine-nucleotide releasing factor
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For Research Use Only. Not For Clinical Use.