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ASTL

Anti-ASTL ProductsBackground
Anti-ASTL Products
- AbPlus™ Anti-ASTL Magnetic Beads (7H2) (VS-0424-XY21)
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- Target: ASTL
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Background
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (T-cells, Macrophages, Glandular and luminal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (RT4)
Interaction
Interacts (via N-terminal domain) with SPACA3; the interaction occurs during fertilization.
Molecular function
Hydrolase, Metalloprotease, Protease
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