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BTN3A3
Anti-BTN3A3 Recombinant Antibody Products
- Recombinant Anti-Human BTN3A3 Antibody (MOB-2964z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, IF, FuncS
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- Recombinant Anti-Human BTN3A3 Antibody Fab Fragment (MOB-2964z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, Neut, FuncS
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- Recombinant Anti-Human BTN3A3 Antibody scFv Fragment (MOB-2964z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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For Research Use Only. Not For Clinical Use.
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (NK-cells, Plasma cells, T-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V)
Interaction
Homodimer.
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