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C8G
Anti-C8G Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Protein class
Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (HMC-1)
Interaction
C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded.
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