Anti-CA6 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is a global leader in oral biology research, delivering top-tier anti-CA6 recombinant antibodies. As the only secreted carbonic anhydrase present in saliva, CA6 is implicated in a range of key processes for maintaining a healthy oral cavity and may be involved in the sense of taste. Creative Biolabs' premium antibodies offer researchers the necessary tools to investigate its roles in the oral cavity, its potential as a biomarker for a range of conditions, and its involvement in carbonation and taste perception.

CA6: The Secreted Salivary Carbonic Anhydrase

CA6 is one of 15 known alpha-carbonic anhydrases. Unlike the other 14 carbonic anhydrases that are cytosolic, mitochondrial or bound to the endoplasmic reticulum, CA6 is a secreted protein. It is expressed in acinar cells of the salivary glands and secreted into saliva in large quantities. In the mouth, the protein is believed to play a number of roles, from maintaining the acidity of dental plaque (protecting against caries) to contributing to the sensation of carbonated ("fizzy") tastes. As a secreted protein, its presence in saliva makes it a good candidate for a non-invasive biomarker for disorders of the salivary glands (such as Sjögren's syndrome) and other systemic diseases.

Alternative Names

CA6; carbonic anhydrase VI; CA-VI; GUSTIN; carbonic anhydrase 6; carbonate dehydratase VI; salivary carbonic anhydrase; secreted carbonic anhydrase

Background

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.

Protein class

Enzymes, FDA approved drug targets, Metabolic proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Melanocytes, Ionocytes, Breast glandular cells)

Immune cell specificity

Group enriched (naive CD8 T-cell, naive CD4 T-cell)

Cell line specificity

Cell line enhanced (Daudi, U-2197)

Molecular function

Lyase

More Types Infomation

Anti-CA6 rAb Products

Creative Biolabs' anti-CA6 recombinant antibodies are engineered for high affinity and specificity. They are fully validated for accurate detection of the CA6 protein in saliva and salivary gland tissue. Optimized for use in key applications such as ELISA for quantitation in saliva and IHC on salivary gland sections, these rAbs offer the performance and reliability that researchers need to drive oral biology and biomarker discovery forward.

Table 1. Featured anti-CA6 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
MHH-145 Recombinant Human Anti-human CA6 Antibody Human Human IgG ELISA, WB, IF, FuncS
MOB-145 Recombinant Anti-human CA6 Antibody Human Mouse IgG WB, FC, FuncS

Customer Reviews

Excellent
Gr**e
Recombinant Anti-human CA6 Antibody
The quality of Creative Biolabs' reagents is outstanding. Their anti-CA6 antibody has given us consistent, reliable results throughout our project looking at the physiology of taste.
13/Oct/2023

rAb Production

To help researchers stay at the forefront of biomarker discovery, Creative Biolabs leverages the latest production technologies to offer the most innovative tools and reagents available. Our anti-CA6 recombinant antibodies are produced as matched pairs and fully validated for robust, sensitive sandwich ELISA development, giving you a ready-to-use biomarker reagent.

Featured Anti-CA6 Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-CA6 recombinant antibody production.

Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-CA6 recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to offering flexible, innovative tools and reagents for the research community. Our anti-CA6 recombinant antibodies are available in a range of customizable modalities, giving researchers around the world the ability to study this unique secreted enzyme and its potential as a biomarker.

CA6 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-CA6 recombinant antibody production and modalities.

Empower your oral biology research and biomarker discovery with Creative Biolabs' industry-leading anti-CA6 recombinant antibodies. Creative Biolabs is known for its high specificity and robust validation, which make our products the ideal tools for everything from basic research to clinical diagnostics. Let our experts help you find the right solution for your project today.

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