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CACNG4

CACNG4 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4) is a Protein Coding gene. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is CACNG8.
Protein class

FDA approved drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SH-SY5Y)

Interaction

Interacts with CACNA1C. Identified in a complex with the L-type calcium channel subunits CACNA1C, CACNA2D1 and either CACNB1 or CACNB2 (PubMed:21127204). Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs) (PubMed:21172611). Interacts with GRIA1 (PubMed:21172611).

Molecular function

Calcium channel, Ion channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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