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CCL8
Anti-CCL8 Recombinant Antibody Products
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- Derivation: Phage display library screening
- Species Reactivity: Human, Predicted to work with: Does not react with Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein class
Cancer-related genes
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Smooth muscle cells)
Immune cell specificity
Immune cell enriched (classical monocyte)
Cell line specificity
Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+ RasG12V, EFO-21, HSkMC)
Interaction
Monomer or homodimer; in equilibrium.
Molecular function
Cytokine, Heparin-binding
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