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CCR4

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For Research Use Only. Not For Clinical Use.


Background

CCR4 (C-C Motif Chemokine Receptor 4) is a Protein Coding gene. Diseases associated with CCR4 include Cutaneous T Cell Lymphoma and Mycosis Fungoides. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CCR5.
CCR4
Protein class

CD markers, FDA approved drug targets, G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (T-cells, Horizontal cells, granulocytes, Plasma cells, Spermatogonia)

Immune cell specificity

Immune cell enriched (T-reg)

Cell line specificity

Cell line enriched (HDLM-2)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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