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Target
Application
Host
Type
Species Reactivity
Expression Host
Derivation
CD27
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Anti-CD27 Products
- Human Anti-CD27 Recombinant Antibody (MOB-096LC) (MOB-096LC)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FuncS, WB
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- Human Anti-CD27 Agonistic Antibody (VS-0724-XY8) (VS-0724-XY8)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Agonistic assays
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- Mouse Anti-CD27 Recombinant Antibody (clone CBL185) (NEUT-323CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, Neut, WB
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- Mouse Anti-CD27 Recombinant Antibody (clone CBL803) (NEUT-322CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, CyTOF, Neut
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- Mouse Anti-CD27 Recombinant Antibody (NEUT-321CQ) (NEUT-321CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Neut, FC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Enables transmembrane signaling receptor activity. Involved in CD27 signaling pathway; negative regulation of apoptotic process; and positive regulation of JNK cascade. Acts upstream of or within negative regulation of T cell apoptotic process. Located in external side of plasma membrane. Is active in plasma membrane. Is expressed in several structures, including femur; hemolymphoid system; intestine; pituitary gland; and reproductive system. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2. Orthologous to human CD27 (CD27 molecule).
Protein class
Cancer-related genes, CD markers, Disease related genes, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Group enriched (Plasma cells, B-cells, T-cells, Melanocytes)
Immune cell specificity
Immune cell enhanced (T-reg)
Cell line specificity
Group enriched (Daudi, U-698)
Interaction
Homodimer. Interacts with SIVA1 and TRAF2.
Molecular function
Receptor
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