CD71

AbPlus Recombinant Antibody Products Formats

Anti-CD71 Recombinant Antibody Products

Mouse Anti-CD71 Recombinant Antibody (clone YTA 74.4.4) (FAMAB-1572CQ)
- Species Reactivity: Mouse
- Type: Mouse IgG1
- Application: FC, IHC
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Mouse Anti-CD71 Antibody (clone YTA 74.4.4), mRNA (FAMAB-1572CQ-mRNA)
- Species Reactivity: Mouse
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Anti-CD71 Immunohistochemistry Kit (VS-0325-XY373)
- Species Reactivity: Human
- Target: CD71
- Application: IHC
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Hi-Affi™ Rabbit Anti-CD71 Recombinant Antibody (clone SI137DS) (MOR-4070)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC
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Hi-Affi™ Rabbit Anti-CD71 Recombinant Antibody (clone SI138DS) (MOR-4071)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IF, IF, FC
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Hi-Affi™ Rabbit Anti-CD71 Recombinant Antibody (clone SI139DS) (MOR-4072)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC
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For Research Use Only. Not For Clinical Use.

Mousetransferrin receptor protein 1, also known as transferrin receptor, Trfr, p90,CD71 and TFRC, is a single-pass type II membrane protein which belongs tothe peptidase M28 family and M28B subfamily. TFRC / CD71 is amembrane-bound protein expressed in larger amounts in proliferating. Thespecific expression of TFRC can represent a diagnostic tool or a therapeutictarget in solid tumours expressing this antigen. Transferrin receptor isnecessary for development of erythrocytes and the nervous system. TFRC / CD71is regulated by cellular iron levels through binding of the iron regulatoryproteins, IRP1 and IRP2, to iron-responsive elements in the 3-UTR.Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker ofmalignant transformation in the pancreas that could be applied as potentialdiagnostic and therapeutic target.