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CD74 & CD22
Engineered Antibody Products
Glyco-Engineering Antibody Products
Tetramer Products
Antibody Magnetic Beads
AbPlus
Recombinant Antibody Products
Functional Antibody Products
Formats
Anti-CD74 & CD22 Recombinant Antibody Products
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) (TAB-183-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- AbPlus™ Anti-Cd22 Magnetic Beads (VS-0724-YC918) (VS-0724-YC918)
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- Target: Cd22
- Target Species: Mouse
- Application: IP, Protein Purification
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- Mouse Anti-CD74 Recombinant Antibody (clone YAML 555.6) (FAMAB-1081CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Mouse Anti-CD74 Recombinant Antibody (VS3-CJ338) (VS3-CJ338)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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- AbPlus™ Anti-CD22 Magnetic Beads (DM13) (VS-0424-XY50)
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- Target: CD22
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF, IHC, IP, FuncS
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- Human Anti-CD74 Recombinant Antibody (TAB-139CL) (TAB-139CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-CD74 Recombinant Antibody (VS-0723-WK70) (VS-0723-WK70)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
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- Human Anti-CD74 Recombinant Antibody (clone Milatuzumab) (VS-0723-WK3)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1, κ
- Application: WB, IHC, IF, FC, ELISA, IP
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- AbPlus™ Anti-CD74 Magnetic Beads (4ALN2) (VS-0424-XY55)
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- Target: CD74
- Target Species: Human
- Application: IP, Protein Purification
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- AbPlus™ Anti-CD74 Magnetic Beads (VS-0724-YC321) (VS-0724-YC321)
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- Target: CD74
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-CD74 Recombinant Antibody (clone In-1) (FAMAB-1683CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG2a
- Application: IP, FC, IHC-Fr
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- Mouse Anti-CD74 Antibody (clone YAML 555.6), mRNA (FAMAB-1081CQ-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-CD74 Antibody (clone In-1), mRNA (FAMAB-1683CQ-mRNA)
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- Species Reactivity: Mouse
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: APC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
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- Rabbit Anti-CD74 Recombinant Antibody (clone JF40-10) (MRO-0316-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Mouse Anti-CD22 Recombinant Antibody (clone K22) (VS3-WK1454)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Human Anti-CD74 Recombinant Antibody (HPAB-0388-FY) (HPAB-0388-FY)
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: FC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: MHHWLLFEMSRHSLE
- Conjugate: APC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: APC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC, WB, IF
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC, WB, IP, IF
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC, IP, IF
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KLPKPPKPVSKMRMATPLL
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KLPKPPKPVSKMRMATPLL
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KLPKPPKPVSKMRMATPLL
- Conjugate: PE
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- Human Anti-CD22 Antibody (clone LL2 (EPB2)), mRNA (FAMAB-1042CQ-mRNA)
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- Species Reactivity: Human
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KLPKPPKPVSKMRMATPLL
- Conjugate: PE
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- Mouse Anti-CD22 Antibody (clone OX97), mRNA (FAMAB-1612CQ-mRNA)
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- Species Reactivity: Mouse
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- Human Anti-CD22 Antibody, mRNA (HPAB-0249-FY-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-CD22 Antibody, mRNA (TAB-003LC-mRNA)
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- Species Reactivity: Human
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Human Anti-CD22 Antibody, mRNA (TAB-198-mRNA) (TAB-198-mRNA)
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- Species Reactivity: Human
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: KPVSKMRMATPLLMQALP
- Conjugate: PE
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
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- Human Anti-CD22 Recombinant Antibody (clone LL2 (EPB2)) (FAMAB-1042CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, FC, IHC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
Compare
- Mouse Anti-CD22 Recombinant Antibody (clone OX97) (FAMAB-1612CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG2a
- Application: WB, FC
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
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- Rabbit Anti-CD22 Recombinant Antibody (clone CBR245) (MOB-260YJL)
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, IP
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- Class: Class II
- Antigen: CD74
- Antigen Species: Human
- Peptide: LPKPPKPVSKMRMATPLLMQALPM
- Conjugate: PE
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- Mouse Anti-CD22 Antibody (clone m5/44), mRNA (FAMAB-0046YC-mRNA)
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- Species Reactivity: Human
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- Recombinant Anti-Human CD22 Antibody Fab Fragment (MOB-1248z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
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- Mouse Anti-NHP CD74 Recombinant Antibody (clone LN-2) (VS-1024-XY110)
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- Species Reactivity: Non-human primate, Human, Mouse
- Type: Mouse IgG1, kappa
- Application: WB, IHC, IF, FC
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- Recombinant Anti-Human CD74 VHH Single Domain Antibody (NAB-466-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: FUNC, FA, IP, ChiP
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- Recombinant Anti-Human CD22 Antibody scFv Fragment (MOB-1248z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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- Human Anti-CD74 Recombinant Antibody; scFv Fragment (HPAB-0388-FY-S(P)) (HPAB-0388-FY-S(P))
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- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: FC
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- Human Anti-CD74 Recombinant Antibody; Fab Fragment (HPAB-0388-FY-F(E)) (HPAB-0388-FY-F(E))
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- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: FC
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- Anti-CD22 Immunohistochemistry Kit (VS-0325-XY357)
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- Species Reactivity: Human
- Target: CD22
- Application: IHC
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- CytoStream™ Mouse Anti-CD74 Recombinant Antibody (clone LN2) (VS-0225-XY71)
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- Species Reactivity: Human
- Type: Mouse IgG1, kappa
- Application: FC
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- Human Anti-CD74 (clone LL1) scFv-Fc Chimera (VS-0325-FY83)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: FC, ELISA, Cyt
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- Anti-CD74 (clone 011 (B))-vc-MMAE ADC (ADC-060CL)
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- Target: CD74
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD74 (clone 006 (A))-vc-MMAE ADC (ADC-061CL)
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- Target: CD74
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.
CD22 is a B-cell-specific transmembrane glycoprotein belonging to the SIGLEC (sialic acid-binding immunoglobulin-like lectin) family. It is encoded by the CD22 gene located on chromosome 19q13.1. CD22 plays a crucial role in B-cell signaling and immune response modulation. It acts primarily as an inhibitory co-receptor that regulates B-cell receptor (BCR) signaling, thereby preventing overactivation of B cells and reducing the risk of autoimmunity. CD22 binds to sialylated glycans and recruits SHP-1 (Src homology region 2 domain-containing phosphatase-1), a phosphatase that dampens signaling cascades.
CD74 (CD74 Molecule) is a Protein Coding gene. Diseases associated with CD74 include Undifferentiated Pleomorphic Sarcoma and Mantle Cell Lymphoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding and amyloid-beta binding.
