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    CD74 & CD22

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    Anti-CD74 & CD22 Products

    • Anti-CD22 (clone hu10F4)-MCC-DM1 ADC (ADC-027LZY)
      • Target: CD22
      • Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD22-mc-vc-PABc-MMAE ADC (ADC-033LZY)
      • Target: CD22
      • Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD22-mc-vc-PABc-NMS249 ADC (ADC-097LZY)
      • Target: CD22
      • Linker: mc-VC-PABc (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: NMS249
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    • Anti-CD22 (clone 5E8)-SMCC-DM1 ADC (ADC-214CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 7A2)-SMCC-DM1 ADC (ADC-215CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v1)-SMCC-DM1 ADC (ADC-216CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v2)-SMCC-DM1 ADC (ADC-217CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v3)-SMCC-DM1 ADC (ADC-219CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
      • Target: CD22
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v3)-MCC-DM1 ADC (ADC-194LZY)
      • Target: CD22
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD22 (clone 10F4v3)-SPP-DM1 ADC (ADC-221CL)
      • Target: CD22
      • Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4)-SMCC-DM1 ADC (ADC-223CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone RFB4)-SMCC-DM1 ADC (ADC-224CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    Background

    CD74 (CD74 Molecule) is a Protein Coding gene. Diseases associated with CD74 include Undifferentiated Pleomorphic Sarcoma and Mantle Cell Lymphoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding and amyloid-beta binding.
    CD74 & CD22
    CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include refractory hematologic cancer and colon lymphoma. Among its related pathways are Immune System and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is VCAM1.
    CD74 & CD22
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