Anti-Human CD22 Recombinant Antibody (TAB-183-F(E))

Name: Anti-Human CD22 Recombinant Antibody (TAB-183-F(E))
SKU: TAB-183-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-183-F(E)

Recombinant monoclonal antibody to CD22. It is an anti-CD22 mouse monoclonal antibody designed for the treatment of cancer.

Tested Data Gene Expression

SDS-PAGE

Figure 1 Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) in SDS-PAGE

SDS-PAGE analysis of TAB-183-F(E) in non-reduced (Lane 1). Gel stained for 30 minutes with Coomassie Blue. And non-reduced protein migrates as 70 kDa.

SEC-HPLC

Figure 2 Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) in HPLC

HPLC analysis of TAB-183-F(E) shows the purity is>95%.

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Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg

Normal Tissue Figure 2 Spleen

Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Mouse

Derivation
Mouse

Type
Fv - disulfide stabilized

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
FuncS, IF, Neut, ELISA, FC, IP, ICC

MW
63.5 kDa

Related Disease
Hairy cell leukemia (HCL)

Product Property

Purity
Purity >95% by SDS-PAGE.

Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Applications

Application Notes
The CD22 antibody has been reported in applications of PK, Cyt.

Target

Alternative Names
Moxetumomab pasudotox;1020748-57-5;CAT-8015;HA22;R490A;BL22 immunotoxin;CD22;CD22 molecule;CD22 antigen;B-cell receptor CD22;sialic acid binding Ig like lectin 2;SIGLEC 2;SIGLEC2;BL-CAM;T-cell surface antigen Leu-14;B-lymphocyte cell adhesion molecule;sia

Gene ID
933

UniProt ID
P20273

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(Creative Biolabs Cat# TAB-183-F(E), RRID: AB_3111855)

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Biosimilar Overview

Please refer to Moxetumomab Pasudotox Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Moxetumomab Pasudotox.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-183-F(E).pdf

MSDS

MSDS - TAB-183-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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CAT	Product Name	Application	Type
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HPAB-0194-LSX-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0194-LSX-S(P))	ELISA	Mouse scFv
HPAB-0195-LSX-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0195-LSX-S(P))	ELISA	Human scFv
HPAB-0370-FY-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0370-FY-S(P))	ELISA	Humanized scFv
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CAT	Product Name	Application	Type
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CAT	Product Name	Application
AGTO-L048E	anti-CD22 immunotoxin RFB4 (scFv)-PE	Cytotoxicity assay, Functional assay
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AGTO-L048G	anti-CD22 immunotoxin RFB4 (scFv)-Gel	Cytotoxicity assay, Functional assay
AGTO-L048R	anti-CD22 immunotoxin RFB4 (scFv)-RTA	Cytotoxicity assay, Functional assay
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CAT	Product Name	Application
TAB-0196CL	Anti-Human CD22 Recombinant Antibody (hLL2)	Inhib, Cyt, FC, WB
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TAB-0197CL-S(P)	Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2-Cys)	ELISA, In vivo
TAB-0196CL-F(E)	Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2)	ELISA, In vivo

CAT	Product Name	Application	Type
TAB-1724CL	Human Anti-CD22 Recombinant Antibody (TAB-1724CL)	Inhib	Chimeric (mouse/human) IgG1, κ
TAB-1724CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P))	Inhib	Mouse scFv
TAB-1724CL-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1724CL-F(E))	Inhib	Chimeric (mouse/human) Fab
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TAB-001LC-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
TAB-1725CL	Human Anti-CD22 Recombinant Antibody (TAB-1725CL)	Block, Cyt, ELISA, FuncS	Humanized IgG
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TAB-1725CL-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1725CL-F(E))	Block, Cyt, ELISA, FuncS	Humanized Fab
TAB-1729CL-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1729CL-F(E))	IF, FC	Humanized Fab
TAB-002LC-F(E)	Anti-Human CD22 Recombinant Antibody Fab Fragment (VM1000)	ELISA, SPR	Humanized antibody

CAT	Product Name	Application	Type
Gly-001LC	Recombinant Anti-Human CD22 Antibody (Fab glycosylation)	ELISA, FC	Mouse antibody

CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
HPAB-0204-LSX	Human Anti-CD22 Recombinant Antibody (clone RFB4-PE38)	Cyt, RIA, FuncS, FC, PK, Neut, ELISA	Chimeric IgG
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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