Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab) (CAT#: TAB-047-F(E))
Recombinant monoclonal antibody fragment Fab to CD22. Bectumomab (marketed under the trade name LymphoScan) is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m. It is used to detect non-Hodgkin's lymphoma.
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Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
Figure 2 Spleen
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
(Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
Specifications
- Immunogen
- A combination of recombinant human CD22 extracellular 25 domain and CHO ceIls engineered to express full-length human CD22 on the ceIl surface
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fab' - G2a - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
- Trade name
- lymphoscan
- CAS
- 158318-63-9
- Generic Name
- Bectumomab
- Related Disease
- Non-Hodgkin's lymphoma (NHL)
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Bectumomab;lymphoscan;158318-63-9;IMMU-LL2-Fab;CD22;CD22 molecule;CD22 antigen;B-cell receptor CD22;sialic acid binding Ig like lectin 2;SIGLEC 2;SIGLEC2;BL-CAM;T-cell surface antigen Leu-14;B-lymphocyte cell adhesion molecule;sialic acid binding Ig-like
- Gene ID
- 933
- UniProt ID
- P20273
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Bectumomab"
DrugMonitor™ Anti-Bectumomab Antibody (VS-1224-YC172)Bectumomab is a murine monoclonal antibody used for treating non-Hodgkin's lymphoma. The DrugMonitor™ Anti-Bectumomab Antibody (VS-1224-YC172) is an anti-drug antibody (ADA) against Bectumomab. This drug-based antibody is raised in mice immunized with the Bectumomab. The anti-Bectumomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bectumomab in samples.
See other products for "CD22"
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IgG Antibodies
Fab Antibodies
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1248z | Mouse IgG1, kappa Anti-CD22 Recombinant Antibody (MOB-1248z) | IF, FC | Mouse IgG1, κ |
| MOB-0349MZ | Mouse Anti-CD22 Recombinant Antibody (clone 5LB129) | ELISA | Mouse IgG1 |
| HPAB-N0324-YC | Mouse Anti-CD22 Recombinant Antibody (HPAB-N0324-YC) | FuncS | Mouse IgG |
| HPAB-N0325-YC | Mouse Anti-CD22 Recombinant Antibody (HPAB-N0325-YC) | FuncS | Mouse IgG |
| ZG-0989F | Mouse Anti-CD22 Recombinant Antibody (clone 3H4) | FC, IHC-Fr, ICC, IHC-Fr | Mouse IgG1 |
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