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CHRNA5

Anti-CHRNA5 Products

Mouse Anti-CHRNA5 Recombinant Antibody (clone 18A6) (MOB-3790z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC
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Hi-Affi™ Rabbit Anti-CHRNA5 Recombinant Antibody (clone DS699AB) (MOR-0699)
- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IP, FC
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Mouse Anti-CHRNA5 Recombinant Antibody (clone 2D2D10) (VS7-HM721)
- Derivation: Mouse
- Species Reactivity: Human, Rat
- Type: Mouse IgG1
- Application: WB, FCM
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Mouse Anti-CHRNA5 Recombinant Antibody (clone 8F11G8) (VS7-HM722)
- Derivation: Mouse
- Species Reactivity: Human, Rat
- Type: Mouse IgG2a
- Application: WB, FCM
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Spermatogonia, Basal prostatic cells, Spermatocytes, Extravillous trophoblasts, Intestinal goblet cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (beta). Interacts with LYPD6 (PubMed:27344019).

Molecular function

Ion channel, Ligand-gated ion channel, Receptor

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