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CK7

Anti-CK7 Products
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ICC
- Mouse Anti-CK7 Recombinant Antibody (clone 5D12) (VS7-HM743)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FCM
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For Research Use Only. Not For Clinical Use.
Background
Keratin 7 (KRT7) is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.