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CLEC16A

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Astrocytes, Early spermatids, Excitatory neurons, Late spermatids, Oligodendrocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (HDLM-2)

Interaction

Interacts with RNF41/NRDP1.

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