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Cationic 2-aminobenzimidazolium hapten 4

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Anti-Cationic 2-aminobenzimidazolium hapten 4 ProductsBackground

Anti-Cationic 2-aminobenzimidazolium hapten 4 Products

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For Research Use Only. Not For Clinical Use.


Background

The positively charged benzimidazolium hapten 4 was designed to elicit a reaction chamber for the Kemp elimination in an antibody-combining site containing (i) a carboxylate group for proton abstraction and (ii) aromatic groups for transition state stabilization. The structural data show that these design goals have been exceptionally well realized in the active site of antibody 34E4.
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