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DC-HIL

Anti-DC-HIL Products
- Mouse Anti-DC-HIL Recombinant Antibody (HPAB-1204LY) (HPAB-1204LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-DC-HIL Recombinant Antibody (HPAB-1205LY) (HPAB-1205LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-DC-HIL Recombinant Antibody; Fab Fragment (HPAB-1205LY-F(E)) (HPAB-1205LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Mouse Anti-DC-HIL Recombinant Antibody; scFv Fragment (HPAB-1205LY-S(P)) (HPAB-1205LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-DC-HIL Recombinant Antibody; Fab Fragment (HPAB-1204LY-F(E)) (HPAB-1204LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Mouse Anti-DC-HIL Recombinant Antibody; scFv Fragment (HPAB-1204LY-S(P)) (HPAB-1204LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.