DHRS9

Antibody Magnetic Beads AbPlus Formats

Anti-DHRS9 Recombinant Antibody Products

Mouse Anti-DHRS9 Recombinant Antibody (clone 41A12) (MOB-2356z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, ICC, IF
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AbPlus™ Anti-DHRS9 Magnetic Beads (VS-0724-YC1046) (VS-0724-YC1046)
- Target: DHRS9
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Paneth cells, Syncytiotrophoblasts, Distal enterocytes, Urothelial cells, Club cells, Respiratory ciliated cells, Early spermatids)

Immune cell specificity

Group enriched (basophil, eosinophil, neutrophil)

Cell line specificity

Cell line enhanced (hTERT-RPE1, HUVEC TERT2, NB-4, THP-1, TIME, U-2197)

Interaction

Homotetramer.

Molecular function

Oxidoreductase

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