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DOT1L
Anti-DOT1L Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Interacts with MLLT10.
Molecular function
Chromatin regulator, DNA-binding, Methyltransferase, Transferase
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