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DPP3

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012]
Protein class

Enzymes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Rod photoreceptor cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Molecular function

Aminopeptidase, Hydrolase, Metalloprotease, Protease

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