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EBV Bcl-2

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Anti-EBV Bcl-2 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The Epstein-Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family, and is one of the most common viruses in humans. Bcl-2 is an anti-apoptotic cell cycle regulator that is highly expressed in EBV-positive lymphomas and may be associated with oncogenesis. During the early lytic cycle of EBV infection, the virus expresses the BHRF1 gene which encodes for a homologus viral Bcl-2 protein. This transmembrane protein may act to prevent apoptosis during EBV infection, thereby maximizing virus particle production and facilitating the establishment of virus persistence.
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