ECD

Antibody Magnetic Beads AbPlus Formats

Anti-ECD Recombinant Antibody Products

AbPlus™ Anti-ECD Magnetic Beads (VS-0724-YC363) (VS-0724-YC363)
- Target: ECD
- Target Species: Human
- Application: IP, Protein Purification
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Anti-ECD Immunohistochemistry Kit (VS-0325-XY721)
- Species Reactivity: Human, Mouse, Rat
- Target: ECD
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Enables histone acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm.

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with TP53, MDM2, TXNIP (PubMed:16849563, 23880345). Interacts (phosphorylated) with PIH1D1. Interacts with RUVBL1 mediating the PIH1D1-independent association with the R2TP complex (PubMed:24656813, 26711270). Interacts with RB1, RBL1 and RBL2; ECD competes with E2F1 for binding to hypophospshorylated RB1 (PubMed:19640839). Interacts with EP300 (PubMed:19919181).

Molecular function

Activator

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