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ELF5
Anti-ELF5 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Breast glandular cells, Collecting duct cells, Breast myoepithelial cells, Alveolar cells type 2, Cytotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (RT4, T-47d)
Molecular function
Activator, DNA-binding
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