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ESPL1
Anti-ESPL1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Protein class
Enzymes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Ionocytes, Squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Interacts with PTTG1. Interacts with RAD21.
Molecular function
Hydrolase, Protease, Thiol protease
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