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ErbB
Loading...Anti-ErbB Products
- Recombinant Anti-human ErbB Antibody (MOB-327)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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- Recombinant Human Anti-human ErbB Antibody Fab Fragment (MHH-327-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
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- Recombinant Human Anti-human ErbB Antibody scFv Fragment (MHH-327-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
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- Recombinant Anti-human ErbB Antibody Fab Fragment (MOB-327-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, WB, FuncS
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- Recombinant Anti-human ErbB Antibody scFv Fragment (MOB-327-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Background
The ErbB family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered member. In humans, the family includes Her1 (EGFR, ErbB1), Her2 (Neu, ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a viral oncogene to which these receptors are homologous: erythroblastic leukemia viral oncogene. Insufficient ErbB signaling in humans is associated with the development of neurodegenerative diseases, such as multiple sclerosis and Alzheimer's Disease, while excessive ErbB signaling is associated with the development of a wide variety of types of solid tumor.