FAT4

Formats

Anti-FAT4 Recombinant Antibody Products

Rabbit Anti-FAT4 Polyclonal Antibody (MRO-1854-CN) (MRO-1854-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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Mouse Anti-FAT4 Recombinant Antibody (VS3-WK1037) (VS3-WK1037)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB
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Mouse Anti-FAT4 Recombinant Antibody (VS3-FY2701) (VS3-FY2701)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene.

Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Inhibitory neurons, Hepatic stellate cells, Microglial cells, Adipocytes, Endothelial cells, Fibroblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC, HUVEC TERT2, TIME)

Interaction

Heterophilic interaction with DCHS1; this interaction affects their respective protein levels. Interacts (via cytoplasmic domain) with MPDZ. Forms a complex with PALS1 and MPDZ.

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