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FKBP6

Anti-FKBP6 Products

Rabbit Anti-FKBP6 Recombinant Antibody (clone R05-4G2) (VS3-FY2005)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
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Hi-Affi™ Rabbit Anti-FKBP6 Recombinant Antibody (clone DS1312AB) (MOR-1312)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, FC
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More Infomation

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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants.

Protein class

Disease related genes, Human disease related genes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Spermatocytes, Late spermatids, Early spermatids, Spermatogonia)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts (via TPR repeats) with HSP90 (By similarity). Interacts with HSP72/HSPA2 and CLTC. Interacts with GAPDH; leading to inhibit GAPDH catalytic activity.

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