FLG

Formats

Anti-FLG Recombinant Antibody Products

Mouse Anti-FLG Recombinant Antibody (clone 38B1) (MOB-1398z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
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Recombinant Mouse Anti-Human FLG Antibody (clone GMH02) (MOB-1521MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IHC-P
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Mouse Anti-FLG Recombinant Antibody (ZG-0351J) (ZG-0351J)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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Mouse Anti-FLG Recombinant Antibody (clone FLG01) (ZG-0588F)
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]

Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Suprabasal keratinocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HaCaT, NTERA-2, TIME, U-2 OS, U-2197, WM-115)

Molecular function

Developmental protein

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