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FMNL1
Anti-FMNL1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (dendritic cells, NK-cells, Langerhans cells, T-cells, monocytes, Macrophages, Plasma cells, B-cells, Kupffer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Karpas-707, MOLT-4, U-266/70)
Interaction
Interacts with RAC1, PFN1 and PFN2 (By similarity). Interacts (activated by RAC1) with SRGAP2 (via SH3 domain); regulates the actin filament severing activity of FMNL1.
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