


GCH1

Anti-GCH1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: WB, ELISA, IF, IHC, IP
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For Research Use Only. Not For Clinical Use.
Background
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Intracellular
Cell type enhanced (Enteroendocrine cells, Hepatocytes)
Immune cell enhanced (non-classical monocyte)
Cell line enhanced (BEWO, Daudi, JURKAT, SH-SY5Y)
Toroid-shaped homodecamer, composed of a dimer of pentamers. The inactive isoforms also form decamers and may possibly be incorporated into GCH1 heterodecamers, decreasing enzyme stability and activity. Interacts with AHSA1 and GCHFR/GFRP.
Allosteric enzyme, Hydrolase