Loading...
GET3
ATPase Get3, which accommodates the hydrophobic tail anchor of clients, has a dual function: promoting tailanchored
protein insertion when glucose is abundant and serving as an ATP-independent holdase chaperone during energy depletion
protein insertion when glucose is abundant and serving as an ATP-independent holdase chaperone during energy depletion
Protein class
Transporters
Predicted location
Intracellular
Single cell type specificity
Group enriched (Hofbauer cells, Syncytiotrophoblasts, Cytotrophoblasts, Extravillous trophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer (By similarity). Component of the Golgi to ER traffic (GET) complex, which is composed of GET1/WRB, CAMLG/GET2 and GET3/TRC40 (PubMed:21444755, 23041287, 24392163, 32910895). Within the complex, CAMLG and GET1 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer (PubMed:32910895). Interacts with CAMLG (via N-terminus) (By similarity). GET3 shows a higher affinity for CAMLG than for GET1 (PubMed:24392163). Interacts with SERP1 and SEC61B (PubMed:17382883, 18477612).
Molecular function
Hydrolase
More Types Infomation
- Recombinant Human Anti-GET3 Antibody (sAB) (PABL-102)
-
- Derivation: Human
- Species Reactivity: S. cerevisiae
- Type: IgG
- Application: WB, ELISA, FuncS
-
- Derivation: Human
- Species Reactivity: S. cerevisiae
- Type: scFv
- Application: WB, ELISA, FuncS
- Human Anti-GET3 Antibody (clone sAB), mRNA (PABL-102-mRNA)
-
- Species Reactivity: S. cerevisiae
-
- Derivation: Human
- Species Reactivity: S. cerevisiae
- Type: Fab
- Application: WB, ELISA, FuncS
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.