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GNMT

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Anti-GNMT Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The GNMT gene encodes for the enzyme glycine N-methyltransferase, which is pivotal in the regulation of methyl group metabolism. This enzyme catalyzes the transfer of methyl groups from S-adenosylmethionine to glycine, producing N-methylglycine and S-adenosylhomocysteine. This process is crucial for maintaining the balance of methyl groups within cells, which impacts DNA methylation and overall gene expression. Mutations or dysfunctions in the GNMT gene can lead to metabolic abnormalities and have been linked to various diseases, highlighting its significance in cellular and metabolic health.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Hepatocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (Hep G2, SCLC-21H, T-47d)

Interaction

Homotetramer.

Molecular function

Methyltransferase, Transferase

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