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GNMT

Anti-GNMT Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, FC, ICC, IF
- Mouse Anti-GNMT Recombinant Antibody (VS3-WK968) (VS3-WK968)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB
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For Research Use Only. Not For Clinical Use.
The GNMT gene encodes for the enzyme glycine N-methyltransferase, which is pivotal in the regulation of methyl group metabolism. This enzyme catalyzes the transfer of methyl groups from S-adenosylmethionine to glycine, producing N-methylglycine and S-adenosylhomocysteine. This process is crucial for maintaining the balance of methyl groups within cells, which impacts DNA methylation and overall gene expression. Mutations or dysfunctions in the GNMT gene can lead to metabolic abnormalities and have been linked to various diseases, highlighting its significance in cellular and metabolic health.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Hep G2, SCLC-21H, T-47d)
Interaction
Homotetramer.
Molecular function
Methyltransferase, Transferase
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