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GPN1

Anti-GPN1 Products
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- Species Reactivity: Human
- Application: IHC-P, WB
- AbPlus™ Anti-GPN1 Magnetic Beads (VS-0724-YC1056) (VS-0724-YC1056)
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- Target: GPN1
- Target Species: Human
- Application: IP, Protein Purification
- Anti-GPN1 Immunohistochemistry Kit (VS-0525-XY2889)
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- Species Reactivity: Human
- Target: GPN1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer with GPN3 (PubMed:21768307). Binds to RNA polymerase II (RNAPII) (PubMed:17643375, PubMed:20864038, PubMed:21844196). Interacts directly with RNAPII subunits RPB4 and RPB7 and the CTD of RPB1 (PubMed:21768307). Interacts with XPA (PubMed:11058119).
Molecular function
Hydrolase
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