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GRIK4
Anti-GRIK4 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ELISA, FC, ICC, IHC
- Mouse Anti-GRIK4 Recombinant Antibody (clone 8H5G5) (VS7-HM1029)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC, ICC, FCM
- Mouse Anti-GRIK4 Recombinant Antibody (clone 8H5H9) (VS7-HM1030)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC, ICC, FCM
- Rabbit Anti-GRIK4 Recombinant Antibody (VS13-YC469) (VS13-YC469)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.
Protein class
FDA approved drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Excitatory neurons, Oligodendrocytes, Astrocytes, Inhibitory neurons, Cone photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HDLM-2, HEL, T-47d)
Interaction
Forms a heteromeric channel with GRIK1 or GRIK3.
Molecular function
Ion channel, Ligand-gated ion channel, Receptor
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