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GRIK4

Formats

Anti-GRIK4 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.
Protein class

FDA approved drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Excitatory neurons, Oligodendrocytes, Astrocytes, Inhibitory neurons, Cone photoreceptor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HDLM-2, HEL, T-47d)

Interaction

Forms a heteromeric channel with GRIK1 or GRIK3.

Molecular function

Ion channel, Ligand-gated ion channel, Receptor

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