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GRM1
Loading...Anti-GRM1 Products
- Rabbit Anti-GRM1 Recombinant Antibody (clone JM11-61) (MRO-0993-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Llama Anti-GRM1 Recombinant Antibody (clone Nb43) (VS-0624-FY10)
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- Species Reactivity: Human
- Type: Lama VHH
- Application: IA
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- Mouse Anti-GRM1 Recombinant Antibody (clone 5E12D8) (VS7-HM1035)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
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- Anti-GRM1 Immunohistochemistry Kit (VS-0525-XY2930)
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- Species Reactivity: Human
- Target: GRM1
- Application: IHC
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- Chicken Anti-GRM1 Polyclonal IgY (BRD-0701MZ)
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- Species Reactivity: Human, Rat, Mouse
- Type: Chicken antibody
- Application: ICC/IF, IHC
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For Research Use Only. Not For Clinical Use.
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Protein class
Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Excitatory neurons, Inhibitory neurons, Rod photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Homodimer; disulfide-linked (PubMed:24603153). The PPXXF motif binds HOMER1, HOMER2 and HOMER3. Interacts with TAMALIN (By similarity). Interacts with RYR1, RYR2, ITPR1, SHANK1 and SHANK3. Interacts with SIAH1 (By similarity).
Molecular function
G-protein coupled receptor, Receptor, Transducer
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