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GSPT1
Loading...Anti-GSPT1 Products
- Anti-GSPT1 Immunohistochemistry Kit (VS-0525-XY2949)
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- Species Reactivity: Human
- Target: GSPT1
- Application: IHC
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- Anti-Rat GSPT1 Immunohistochemistry Kit (VS-0525-XY2950)
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- Species Reactivity: Human, Rat
- Target: GSPT1
- Application: IHC
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- Anti-Mouse GSPT1 Immunohistochemistry Kit (VS-0525-XY2951)
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- Species Reactivity: Human, Mouse, Rat, Canine, Bovine, Frog
- Target: GSPT1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex (PubMed:19417104). The ETF1-GSPT1 complex interacts with JMJD4 (PubMed:24486019). Interacts with PABPC1 (By similarity). Interacts with SHFL (PubMed:30682371).
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