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H3C14

Anti-H3C14 Products
- Rat Anti-H3C14 Recombinant Antibody (VS-0224-XY57) (VS-0224-XY57)
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- Type: Rat IgG
- Application: ELISA, WB, ICC
- Anti-H3C14 Immunohistochemistry Kit (VS-0525-XY3034)
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- Species Reactivity: Human
- Target: H3C14
- Application: IHC
- Anti-Mouse H3C14 Immunohistochemistry Kit (VS-0525-XY3035)
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- Species Reactivity: Human, Mouse, Rat
- Target: H3C14
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.