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HPR
Anti-HPR Recombinant Antibody Products
- Mouse Anti-HPR Recombinant Antibody (clone 35B4) (MOB-3716z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Hepatocytes, Smooth muscle cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (Hep G2)
Molecular function
Serine protease homolog
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