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For Research Use Only. Not For Clinical Use.
Metabolic proteins
Intracellular, Membrane (different isoforms)
Cell type enhanced (Proximal enterocytes)
Low immune cell specificity
Cell line enhanced (HDLM-2)
Monomer. Binds nuclear transport receptors XPO4, IPO5/RANBP5, IPO7, IPO9 and KPNB1 as well as GCN1L1/GCN1 and LRPPRC probably through their HEAT repeats. Binds NCOA5/CIA. Isoform 2 binds the proteasome subunit PSMD4/s5a through its N-terminus. (Microbial infection) Interacts with HIV-1 Tat (via activation domain).
Developmental protein, Oxidoreductase