+ Filter
Loading...
Anti-5-HT1A Recombinant Antibody Products
Anti-HTR1A Recombinant Antibody Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Creative Biolabs provides anti-5-HT1A recombinant antibody products to support critical projects worldwide, leveraging advanced platforms and a team of experienced experts. Our extensive project experience and deep expertise enable us to deliver precise and efficient solutions, allowing our customers to achieve their research goals easily and excellently.
5-HT1A: A Crucial Target in Psychiatric Disorders
The 5-HT1A receptors, encoded by the 5-HT1A gene, play a vital role in the body's serotonin system, acting at both pre- and post-synaptic sites in various brain regions. Increasing evidence underscores their significant impact on a variety of psychiatric disorders, including mood and anxiety disorders, as well as their involvement in suicidal behavior and psychoses. Given the critical influence of the 5-HT1A gene on mental health, it is imperative to develop more effective therapeutic strategies to regulate its expression, thereby offering potential benefits for treating a range of psychiatric conditions.
Anti-5-HT1A Recombinant Antibody Products
Our mission is to boost research and innovation by offering premium anti-5-HT1A recombinant antibodies at exceptional value, coupled with top-notch technical support. The list below contains several anti-5-HT1A recombinant antibodies.
| Cat. No. | Product Name | Target Species | Host Species | Applications |
| MOB-1944z | Mouse Anti-5-HT1A Recombinant Antibody (clone 13F2) | Human | Mouse IgM, κ | WB, IHC |
Creative Quality Control
Our commitment is to empower the biopharmaceutical community by advancing research and development through unparalleled product quality and exceptional support. We prioritize customer satisfaction by rigorously maintaining a comprehensive quality management system. This ensures our products not only meet but surpass industry standards, thereby streamlining the drug development process and delivering superior value to our customers.
Customer Reviews
Excellent
Ts***gMouse Anti-5-HT1A Recombinant Antibody (clone 13F2) (CAT#: MOB-1944z)
I utilized this antibody to assess 5-HT1A expression in brainstem sections, which included the pons and midbrain regions. The recommended concentration was perfect for my assay, yielding clear results without any background interference.
19/May/2023
Excellent
User 18*****3Mouse Anti-5-HT1A Recombinant Antibody (clone 13F2) (CAT#: MOB-1944z)
I assessed this antibody’s specificity using tissue samples from different species before launching my experiment. The results affirmed its exceptional reactivity and specificity to the human species, as even small sample amounts produced a significant response.
5/Feb/2024
Excellent
User 19*****1Mouse Anti-5-HT1A Recombinant Antibody (clone 13F2) (CAT#: MOB-1944z)
In my IHC assay, the mouse anti-5-HT1A recombinant antibody has a nice performance in labeling the 5-HT1A within the brain sections. At the suggested concentration, the observation is clearer than other anti-5-HT1A antibodies purchased from another company. I am impressed with this purchase.
27/Oct/2023
Anti-5-HT1A Recombinant Antibody Production
Based on our advanced mammalian cell expression platform (serum-free), we provide a full around of services ranging from gene synthesis to antibody production, enabling scalable and high-quality anti-5-HT1A recombinant antibody delivery for global customers. With more than five years of specialized experience in process optimization, we ensure a fast and cost-effective supply of antibodies in various quantities, all within a short turnaround time.
Featured rAb Production Platforms
Fig.1 Milligram-scale anti-5-HT1A recombinant antibody production.
Fig.2 Gram-scale anti-5-HT1A recombinant antibody production.
Anti-5-HT1A Recombinant Antibody Modalities
At Creative Biolabs, we specialize in providing state-of-the-art recombinant antibodies tailored to meet the diverse needs of the research community. Our anti-5-HT1A antibodies are available in multiple formats, including full-length, Fab, scFv, etc. With a wealth of experience and a commitment to precision in antibody engineering, we are well-equipped to offer bespoke antibody solutions that align perfectly with your research objectives.
Fig.3 Full-Length Anti-5-HT1A Recombinant Antibody Production and Modalities.
Alternative Names
5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; ADRB2RL1; ADRBRL1; G-21; Serotonin receptor 1A; Guanine Nucleotide-Binding Regulatory Protein-Coupled Receptor; 5-HT1a Receptor; PFMCD.
Background
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
Protein class
Disease related genes, FDA approved drug targets, G-protein coupled receptors, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (NTERA-2, SCLC-21H)
Interaction
Heterodimer; heterodimerizes with GPER1. Interacts with YIF1B (By similarity).
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
Drug Information Targeting 5-HT1A (Under Development)
Table 1. 5-HT1A-targeted drug information (Under development).
| Company | Research Phase | Condition | Indication |
| AbbVie | Phase III | Parkinson's disease | Treatment of early and intermediate stages of Parkinson's disease |
| Pfizer | Phase III | Depression | Treatment of depression |
| Pfizer | Phase II | Anxiety disorders | Treatment of anxiety |
| PsychoGenics | Phase II | Attention deficit hyperactivity disorder (ADHD) | In adult patients |
| Amarantus BioScience | Phase II | Cognitive disorders | To improve cognitive impairment in adult schizophrenic patients |
| Amarantus BioScience | Phase II | Dementia, Alzheimer type | Treatment of elderly patients with Alzheimer's dementia who are aggressive |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Drug Information Targeting 5-HT1A (Launched)
Table 2. 5-HT1A targeted-drug information (Launched).
| Company | Research Phase | Condition | Indication |
| Bristol-Myers Squibb | Launched - 2006 | Agitation | Treatment of agitation associated with schizophrenia or bipolar disorder, manic or mixed |
| Otsuka Pharmaceutical | Launched - 2016 | Autism spectrum disorders | Treatment of irritability associated with autistic disorder in pediatric patients aged 6 to 17 years |
| Otsuka Pharmaceutical | Launched - 2020 | Bipolar disorder | Suppression of recurrence and relapse of mood episodes in bipolar I disorder |
| Lundbeck | Launched - 2023 | Bipolar disorder (I) | Maintenance monotherapy treatment of bipolar I disorder in adults |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
For further information on our anti-5-HT1A recombinant antibody offerings, we invite you to contact us at your convenience.