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HUWE1

Anti-HUWE1 Products

Recombinant Mouse Anti-Human HUWE1 Antibody (clone BY92) (MOB-0686MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ICC, IF, WB
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Anti-HUWE1 Immunohistochemistry Kit (VS-0325-XY1081)
- Species Reactivity: Human, Mouse, Rat
- Target: HUWE1
- Application: IHC
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Anti-Mouse HUWE1 Immunohistochemistry Kit (VS-0525-XY3362)
- Species Reactivity: Human, Mouse, Rat
- Target: HUWE1
- Application: IHC
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Anti-Human HUWE1 Immunohistochemistry Kit (VS-0525-XY3361)
- Species Reactivity: Human
- Target: HUWE1
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (Granulosa cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with isoform p14ARF of CDKN2A which strongly inhibits HUWE1 ubiquitin ligase activity. Interacts with MYCN, POLB and CDC6. Interacts with isoform 2 of PA2G4. Interacts with NR1D1 (PubMed:20534529). Interacts with AMBRA1 (PubMed:30217973).

Molecular function

DNA-binding, Transferase

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