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Histone H2B

Anti-Histone H2B Products

Rabbit Anti-HTB1 (pT129) Recombinant Antibody (clone R04-3T6) (VS3-WK2112)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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Rabbit Anti-Histone H2B Recombinant Antibody (clone TH29DS) (MOR-4521)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, ICC, FC
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For Research Use Only. Not For Clinical Use.

Background

Histone H2B is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and long N-terminal and C-terminal tails, H2B is involved with the structure of the nucleosomes.

Enables DNA binding activity. Involved in chromatin assembly or disassembly; negative regulation of transcription by RNA polymerase II; and postreplication repair. Part of nucleosome and replication fork protection complex. Orthologous to several human genes including H2BC11 (H2B clustered histone 11); H2BC12 (H2B clustered histone 12); and H2BC13 (H2B clustered histone 13).