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IDS

Anti-IDS Products
- Mouse Anti-IDS Recombinant Antibody (clone 31A6) (MOB-2161z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, FC, IF, IHC
- Mouse Anti-NHP IDS Recombinant Antibody (clone OTI4G2) (VS-1024-XY269)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IHC, IF, FC
- Anti-IDS Immunohistochemistry Kit (VS-0525-XY3391)
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- Species Reactivity: Human
- Target: IDS
- Application: IHC
- Anti-Mouse IDS Immunohistochemistry Kit (VS-0525-XY3392)
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- Species Reactivity: Human, Mouse, Rat, Canine, Monkey
- Target: IDS
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:28593992). The 58-kDa mature form is composed of two chains resulting from proteolitic processing, the 42-kDa chain and the 14-kDa chain that remain stably associated and form the 58-kDa intermediate form which is enzymatically active (PubMed:28593992).
Molecular function
Hydrolase
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