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IFI35

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For Research Use Only. Not For Clinical Use.


Background

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Granulosa cells, Paneth cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG)

Interaction

Homodimer (PubMed:8288566, PubMed:10950963). Also interacts with BATF (PubMed:8954125). Interacts with TRIM21 (PubMed:26342464). Interacts with NMI; the interaction is direct and is facilitated by TRIM21 (PubMed:10779520, PubMed:10950963, PubMed:26342464).

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