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IFIT3
Anti-IFIT3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
IFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3) is a Protein Coding gene. Diseases associated with IFIT3 include Systemic Lupus Erythematosus. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is IFIT2.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Adipocytes, Ductal cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V)
Interaction
Component of an interferon-dependent multiprotein complex, at least composed of IFIT1, IFIT2 and IFIT3 (PubMed:21642987). Interacts with IFIT1 and IFIT2 (PubMed:21190939, PubMed:21642987). Interacts (via N-terminus) with MAVS, TBK1, TRAF6 and DDX58 (PubMed:21813773). Interacts with COPS5 (PubMed:17050680).
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