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IL17A & TNF
Loading...Anti-IL17A & TNF Products
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IHC, ELISA, FC
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- Derivation: Human
- Species Reactivity: Human
- Type: [V-kappa]2 - Fc
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, ELISA, IP, FC, FuncS, Neut, IF
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, IHC, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Cow
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human, Monkey, Canine
- Type: Human IgG
- Application: Neut, ELISA, WB
- Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-048ZJ-F(E)) (TAB-048ZJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA, Neut
- Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-078ZJ-F(E)) (TAB-078ZJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Block, Neut
- Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-079ZJ-F(E)) (TAB-079ZJ-F(E))
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- Species Reactivity: Rat, Mouse, Human
- Type: Human Fab
- Application: ELISA, Block, Neut
- Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-080ZJ-F(E)) (TAB-080ZJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Block, Neut
- Anti-Human TNF Recombinant Antibody (CDP571) (TAB-110CQ)
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (B5) (TAB-111CQ)
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- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
- Human Anti-TNF Recombinant Antibody (TAB-114CQ) (TAB-114CQ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Inhib
- Human Anti-TNF Recombinant Antibody (TAB-115CQ) (TAB-115CQ)
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- Derivation: Humanized
- Species Reactivity: Human, Rhesus macaque, Cynomolgus, Canine
- Type: Humanized antibody
- Application: ELISA, FC, Neut
- Mouse Anti-TNF Recombinant Antibody (clone 18C3) (MOB-1076z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FuncS
- Anti-Human TNF Recombinant Antibody (TAB-118CQ) (TAB-118CQ)
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: FC, ELISA
- Human Anti-TNF Recombinant Antibody (TAB-119CQ) (TAB-119CQ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, BL
- Anti-Human TNF Recombinant Antibody (TAB-396CQ) (TAB-396CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Human Anti-TNF Recombinant Antibody (TAB-397CQ) (TAB-397CQ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (TAB-398CQ) (TAB-398CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (TAB-399CQ) (TAB-399CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: WB
- Anti-Human TNF Recombinant Antibody (TAB-400CQ) (TAB-400CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-131CQ-F(E)) (TAB-131CQ-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-TNF Recombinant Antibody (TAB-401CQ) (TAB-401CQ)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
- Human Anti-TNF Recombinant Antibody (TAB-402CQ) (TAB-402CQ)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
- Anti-Human TNF Recombinant Antibody Fab Fragment (G1) (TAB-140CQ-F(E))
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- Species Reactivity: Human
- Type: Human antibody
- Application: FC, Neut
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-141CQ-F(E)) (TAB-141CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-142CQ-F(E)) (TAB-142CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-143CQ-F(E)) (TAB-143CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-144CQ-F(E)) (TAB-144CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
- Anti-Human TNF Recombinant Antibody Fab Fragment (mAb2071) (TAB-145CQ-F(E))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, Neut, WB
- Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-396CQ-F(E)) (TAB-396CQ-F(E))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-397CQ-F(E)) (TAB-397CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-398CQ-S(P)) (TAB-398CQ-S(P))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-399CQ-S(P)) (TAB-399CQ-S(P))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-400CQ-S(P)) (TAB-400CQ-S(P))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-401CQ-S(P)) (TAB-401CQ-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (TAB-404CQ) (TAB-404CQ)
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- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA
- Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) (TAB-402CQ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (XENP6401) (TAB-405CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-404CQ-S(P)) (TAB-404CQ-S(P))
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- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA, WB
- Anti-Human TNF Recombinant Antibody Fab Fragment (2SD4) (TAB-133CQ-F(E))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
- Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-396CQ-S(P)) (TAB-396CQ-S(P))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-397CQ-S(P)) (TAB-397CQ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Anti-Human TNF Recombinant Antibody Fab Fragment (hMAK195) (TAB-134CQ-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, Neut
- Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) (TAB-135CQ-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human antibody
- Application: ELISA, Neut
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) (TAB-136CQ-F(E))
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- Species Reactivity: Human, Rabbit
- Type: Human Fab
- Application: ELISA, Block
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-137CQ-F(E)) (TAB-137CQ-F(E))
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- Species Reactivity: Human, Cynomolgous macaque
- Type: Human Fab
- Application: ELISA, FC, IF
- Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-138CQ-F(E)) (TAB-138CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IF
- Anti-Human TNF Recombinant Antibody (TAB-120CQ) (TAB-120CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized antibody
- Application: ELISA, Neut
- Anti-Human TNF Recombinant Antibody (TAB-121CQ) (TAB-121CQ)
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Block, Neut
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- Species Reactivity: Rat, Mouse, Human
- Type: Human IgG1
- Application: ELISA, Block, Neut
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Block, Neut
- Anti-Human TNF Recombinant Antibody scFv Fragment (XENP6401) (TAB-405CQ-S(P))
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- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody Fab Fragment (CDP571) (TAB-110CQ-F(E))
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody Fab Fragment (B5) (TAB-111CQ-F(E))
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- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
- Anti-Human TNF Recombinant Antibody scFv Fragment (CDP571) (TAB-110CQ-S(P))
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Anti-Human TNF Recombinant Antibody scFv Fragment (B5) (TAB-111CQ-S(P))
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- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
- Anti-Human TNF Recombinant Antibody Fab Fragment (A10G10) (TAB-112CQ-F(E))
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- Species Reactivity: Human
- Application: ELISA, WB
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut, FunS
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
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- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
- Anti-Human TNFα/RANKL Recombinant Antibody scFv Fragment (8G12) (TAB-311CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
- Rabbit Anti-TNF Recombinant Antibody; Fab Fragment (TAB-139CQ-F(E)) (TAB-139CQ-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Single domain antibody
- Application: ELISA, Inhib
- Anti-Human TNF Recombinant Antibody Fab Fragment (MAK195) (TAB-132CQ-F(E))
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- Species Reactivity: Human
- Application: ELISA, Neut
- Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) (TAB-271CQ-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
- Anti-Human TNF Recombinant Antibody (Vh5/Vk12) (TAB-116CQ)
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- Species Reactivity: Human
- Application: ELISA
- Anti-Human TNF Recombinant Antibody (TAB-117CQ) (TAB-117CQ)
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- Species Reactivity: Human
- Application: ELISA, WB
- Anti-Human TNF Recombinant Antibody (A10G10) (TAB-112CQ)
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- Species Reactivity: Human
- Application: Neut, ELISA, WB
- Anti-Human TNFα/RANKL Recombinant Antibody Fab Fragment (8G12) (TAB-311CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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- Species Reactivity: Human, Monkey, Canine
- Type: Human Fab
- Application: Neut, ELISA, WB
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- Species Reactivity: Cynomolgus, Human
- Type: Mouse scFv
- Application: ELISA, Neut
- Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-030ZJ-F(E)) (TAB-030ZJ-F(E))
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- Species Reactivity: Cynomolgus, Human
- Type: Mouse Fab
- Application: ELISA, Neut
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- Scaffold Name: Kunitz domains
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
- 10-FnIII scaffold protein anti-Human TNFα (SFN-L026)
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- Scaffold Name: 10-FnIII
- Target: TNFα
- Species Reactivity: Human
- Derivation: mRNA Display
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- Scaffold Name: Z-domain of protein A
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
- Ubiquitin scaffold protein anti-TNFα (SUB-L209)
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- Scaffold Name: Ubiquitin
- Target: TNFα
- Derivation: Phage display
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, IHC, FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, IHC, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Bovine Anti-TNF Recombinant Antibody (TAB-623CL) (TAB-623CL)
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- Species Reactivity: Human
- Type: Bovine IgG
- Application: Neut
- Anti-TNFα Recombinant Antibody (TAB-718) (TAB-718)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: F(ab')2 - G3 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Targets: IL17A & TNF
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.


Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
