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IL17A & TNF

Anti-IL17A & TNF Products
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
- Mouse Anti-TNF Recombinant Antibody (clone 18C3) (MOB-1076z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, FuncS
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IHC, ELISA, FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, ELISA, IP, FC, FuncS, Neut, IF
- AbPlus™ Anti-TNF Magnetic Beads (VS-0724-YC1214) (VS-0724-YC1214)
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- Target: TNF
- Target Species: Human
- Application: IP, Protein Purification
- AbPlus™ Anti-IL17A Magnetic Beads (41809) (VS-0424-XY147)
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- Target: IL17A
- Target Species: Human
- Application: IP, Protein Purification
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
- Rabbit Anti-TNF Recombinant Antibody (VS-0322-LC36) (VS-0322-LC36)
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- Species Reactivity: Canine, Human
- Application: ELISA
- Mouse Anti-TNF Recombinant Antibody (VS3-FY2899) (VS3-FY2899)
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- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: WB, IHC
- Human Anti-IL17A Recombinant Antibody (VS-0624-FY63) (VS-0624-FY63)
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- Type: Human IgG
- Application: ELISA, Neut, IHC
- Mouse Anti-Tnf Recombinant Antibody (clone 8C11) (VS-0724-XY88)
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- Species Reactivity: Mouse
- Type: Mouse IgG2c
- Application: ELISA, BLI, Neut
- Mouse Anti-IL17 Recombinant Antibody (clone 10F7M11) (VS-0724-XY82)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-TNF Recombinant Antibody (clone 2H7) (VS-0724-XY92)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Neut
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- AbPlus™ Anti-TNF Magnetic Beads (4H31) (VS-0424-XY256)
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- Target: TNF
- Target Species: Human, Cynomolgus, Rhesus
- Application: IP, Protein Purification
- Human Anti-IL17A Recombinant Antibody (clone 7H9) (VS-0323-CJ29)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, SPR, Inhib
- Human Anti-IL17A Recombinant Antibody (clone 8D3) (VS-0323-CJ30)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, SPR, IA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
- Human Anti-IL17A Recombinant Antibody (clone 9NT) (VS-0323-CJ31)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, SPR, IA, Inhib
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
- Human Anti-IL17A Recombinant Antibody (clone 9NS) (VS-0323-CJ32)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, SPR, IA, Inhib
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
- Mouse Anti-TNF Recombinant Antibody (VS3-CJ263) (VS3-CJ263)
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- Species Reactivity: Human, Mouse, Rat
- Application: WB, IHC
- Human Anti-IL17A Antibody (clone H1-2/L7), mRNA (HPAB-M0105-YC-mRNA)
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- Species Reactivity: Human
- Mouse Anti-TNF Recombinant Antibody (clone 2A9B9) (VS3-XY1528)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
- Human Anti-IL17A Antibody (clone H3-1/L5), mRNA (HPAB-M0106-YC-mRNA)
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- Species Reactivity: Human
- Mouse Anti-TNF Recombinant Antibody (VS3-WK1391) (VS3-WK1391)
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: IHC-P, WB
- Human Anti-IL17A Antibody (clone H3-1/L11), mRNA (HPAB-M0107-YC-mRNA)
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- Species Reactivity: Human
- Rat Anti-TNF Recombinant Antibody (clone 4AMP6-XT22) (VS3-WK1526)
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- Derivation: Rat
- Species Reactivity: Mouse
- Type: Rat IgG1, κ
- Application: IF, FC
- Human Anti-TNF Recombinant Antibody (clone αTNF-H9G1) (VS-0323-XY35)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-IL17A Antibody (clone H3-3/L7), mRNA (HPAB-M0108-YC-mRNA)
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- Species Reactivity: Human
- Human Anti-TNF Recombinant Antibody (clone T7) (VS-0423-CJ42)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IP, IF
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC-P, IF
- Mouse Anti-IL17A Recombinant Antibody (clone BL23) (VS3-WK1008)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IF, FC
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- Species Reactivity: Bovine
- Type: Mouse IgG2b
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
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- Species Reactivity: Pig, Horse, Sheep, Bovine, Human, Rat
- Type: Rabbit IgG
- Application: ELISA, WB
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
- Human Anti-IL17A Antibody, mRNA (Gly-077LC-mRNA)
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- Species Reactivity: Human
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Human Anti-IL17A Antibody (clone Fab6785), mRNA (PABL-238-mRNA)
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- Species Reactivity: Human
- Mouse Anti-TNF Recombinant Antibody (clone 3B10) (HPAB-1564WJ)
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, Neut
- Human Anti-IL17A Antibody (clone H1-2/L5), mRNA (HPAB-M0104-YC-mRNA)
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- Species Reactivity: Human
- Mouse Anti-TNF Recombinant Antibody (clone hTNF40) (HPAB-A1314-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FuncS
- Mouse Anti-IL17A Recombinant Antibody (HPAB-AP683-YC) (HPAB-AP683-YC)
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse IgG
- Application: ELISA, Neut
- Human Anti-TNF Recombinant Antibody (clone chTNF40) (HPAB-A1315-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: FuncS
- Mouse Anti-TNF Recombinant Antibody (FAMAB-0709WJ) (FAMAB-0709WJ)
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- Derivation: Chimeric
- Species Reactivity: Feline
- Type: Mouse IgG
- Application: ELISA, WB
- Mouse Anti-IL17A Recombinant Antibody (HPAB-1747-FY) (HPAB-1747-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Human Anti-TNF Recombinant Antibody (clone D2E7) (HPAB-A1379-YJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Neut, IHC
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC-P, IF
- Mouse Anti-IL17A Recombinant Antibody (HPAB-0460-YJ) (HPAB-0460-YJ)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, Inhib
- Human Anti-TNF Antibody (clone TNFa#1), mRNA (HPAB-S0141-YC-mRNA)
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- Species Reactivity: Human
- Human Anti-IL17A Recombinant Antibody (HPAB-0461-YJ) (HPAB-0461-YJ)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG
- Application: ELISA, Inhib
- Human Anti-TNF Antibody (clone TNFa#2), mRNA (HPAB-S0142-YC-mRNA)
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- Species Reactivity: Human
- Human Anti-TNF Antibody (clone TNFa#3), mRNA (HPAB-S0143-YC-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-IL17A Recombinant Antibody (clone A13M); scFv Fragment (HPAB-0459-YJ-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, Neut, FuncS
- Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-1747-FY-F(E)) (HPAB-1747-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
- Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0461-YJ-F(E)) (HPAB-0461-YJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized Fab
- Application: ELISA, Inhib
- Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-AP683-YC-S(P)) (HPAB-AP683-YC-S(P))
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse scFv
- Application: ELISA, Neut
- Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0460-YJ-F(E)) (HPAB-0460-YJ-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, Inhib
- Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-1747-FY-S(P)) (HPAB-1747-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
- Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-AP683-YC-F(E)) (HPAB-AP683-YC-F(E))
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- Species Reactivity: Human, Cynomolgus
- Type: Mouse Fab
- Application: ELISA, Neut
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- Target: IL-17A
- Species Reactivity: Human
- Cytokine 1: IL22
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: IgG-IL22
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
- Anti-Porcine TNF Immunohistochemistry Kit (VS-0525-XY7349)
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- Species Reactivity: Human, Mouse, Porcine, Monkey, Rabbit, Sheep
- Target: TNF
- Application: IHC
- Anti-Rabbit TNF Immunohistochemistry Kit (VS-0525-XY7354)
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- Species Reactivity: Human, Mouse, Rat, Canine, Rabbit, Zebrafish
- Target: TNF
- Application: IHC
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- Species Reactivity: Human
- Type: Human IgG
- Application: Antigen-Sweeping In Vivo.
- Mouse Anti-TNF Recombinant Antibody (VS7-0425-WR1008) (VS7-0425-WR1008)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Anti-Human TNF Immunohistochemistry Kit (VS-0525-XY7352)
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- Species Reactivity: Human, Porcine, Monkey
- Target: TNF
- Application: IHC
- Anti-TNF Immunohistochemistry Kit (VS-0325-XY2313)
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- Species Reactivity: Human, Mouse
- Target: TNF
- Application: IHC
- Anti-Mouse TNF Immunohistochemistry Kit (VS-0525-XY7348)
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- Species Reactivity: Human, Mouse, Rat, Canine, Rabbit
- Target: TNF
- Application: IHC
- Anti-Fish TNF Immunohistochemistry Kit (VS-0525-XY7355)
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- Species Reactivity: Fish
- Target: TNF
- Application: IHC
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- Species Reactivity: Human
- Type: Rat IgG1 kappa
- Application: Antigen-Sweeping In Vivo.
- Anti-Rat TNF Immunohistochemistry Kit (VS-0525-XY7353)
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- Species Reactivity: Human, Rat
- Target: TNF
- Application: IHC
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- Species Reactivity: Mouse, Rat, Rabbit
- Type: Armenian Hamster IgG
- Application: ELISA, FC, Neut, IP, WB
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- Species Reactivity: Human
- Type: Mouse IgG1, kappa
- Application: FC
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- Antibody Host: Mouse
- Antibody Reactivity: Human
- Human Anti-IL17A (clone Antibody 7) scFv-Fc Chimera (VS-0325-FY96)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ELISA, Inhib
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- Antibody Host: Human
- Antibody Reactivity: Human
- Anti-IL17A Immunohistochemistry Kit (VS-0525-XY3489)
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- Species Reactivity: Human
- Target: IL17A
- Application: IHC
- Human Anti-TNF (clone BPC1500) scFv-Fc Chimera (VS-0125-FY32)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ELISA, Neut
- Anti-Human IL17A Immunohistochemistry Kit (VS-0525-XY3490)
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- Species Reactivity: Human, Monkey
- Target: IL17A
- Application: IHC
- Anti-Mouse IL17A Immunohistochemistry Kit (VS-0525-XY3491)
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- Species Reactivity: Human, Mouse, Rat
- Target: IL17A
- Application: IHC
- CytoStream™ Mouse Anti-TNF Recombinant Antibody (clone MAb11) (VS-0225-XY215)
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- Species Reactivity: Human, Rhesus, Cynomolgus, Baboon
- Type: Mouse IgG1, kappa
- Application: FC
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For Research Use Only. Not For Clinical Use.
Background
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis