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Ubiquitin anti-TNF (SUB-L209)

The ubiquitin that bound TNFα was isolated from the library using Phage display techonology. After affinity maturation, ubiquitin variants were identified having affinities (KD=1 μM) for TNFα as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      
Datasheet
Specifications
Scaffold Name
Ubiquitin
Origin
Ubiquitin-like proteins
Core Structure
α/β (76)
Variable Regions
8 aa
Target
TNFα
Expression Host
E. coli
Affinity Constant
1 μM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
ubiquitin-like proteins; ubiquitin; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Entrez Gene ID
7124
UniProt ID
P01375

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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