Recombinant Human Antibody (A2) is capable of binding to TNFA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TNFA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TNFA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 A graph showing neutralization of in vitro TNF cytotoxicity by murine A2. Control: murine IgG1 anti-lipid A mAb (8A1) with natural human TNF.
Figure 2 Graph showing that mAb A2 inhibits or neutralizes TNF produced by chimpanzee monocytes and rhTNFα.
Figure 3 Graph showing results of a cross-blocking epitope ELISA with murine A2 (mA2) antibody.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-051 | Recombinant Anti-human TNF VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
TAB-412CQ | Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) | ELISA, Inhib | Single domain antibody |
TAB-413CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18) | ELISA, WB, Neut | Single domain antibody |
TAB-414CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL11) | ELISA, WB, Neut | Single domain antibody |
TAB-415CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) | ELISA, WB, Neut, FunS | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-006 | Anti-Human TNF Recombinant Antibody (Infliximab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
TAB-402CQ | Human Anti-TNF Recombinant Antibody (TAB-402CQ) | ELISA | Chimeric (mouse/human) IgG |
TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
TAB-402CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-623CL | Bovine Anti-TNF Recombinant Antibody (TAB-623CL) | Neut | Bovine IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-124CQ | Human Anti-TNF Recombinant Antibody (TAB-124CQ) | FuncS, Neut | Humanized antibody |
TAB-125CQ | Human Anti-TNF Recombinant Antibody (TAB-125CQ) | ELISA, Neut | Humanized antibody |
TAB-126CQ | Human Anti-TNF Recombinant Antibody (TAB-126CQ) | ELISA, Neut | Humanized antibody |
TAB-127CQ | Human Anti-TNF Recombinant Antibody (TAB-127CQ) | ELISA, Neut | Humanized antibody |
TAB-128CQ | Human Anti-TNF Recombinant Antibody (TAB-128CQ) | ELISA, FuncS | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-112CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment (A10G10) | ELISA, WB | |
TAB-116CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment (Vh5/Vk12) | ELISA | |
TAB-117CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment (TSK114) | ELISA | |
TAB-271CQ-S(P) | Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) | ELISA, WB | Rabbit scFv |
TAB-112CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (A10G10) | ELISA, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-111CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (B5) | ELISA, WB | Human antibody |
TAB-113CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-113CQ-F(E)) | ELISA | Human Fab |
TAB-135CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) | ELISA, Neut | Human antibody |
TAB-136CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) | ELISA, Block | Human Fab |
TAB-137CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-137CQ-F(E)) | ELISA, FC, IF | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-083LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
Gly-085LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
Gly-086LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-087LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-088LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-083LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-085LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
Gly-163LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-086LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-087LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0609MZ | Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2057CQ | Rat Anti-Tnf Recombinant Antibody (clone XT3) | Block, ELISA, IHC, WB | Rat IgG1 |
NEUT-2070CQ | Mouse Anti-TNF Recombinant Antibody (clone 4F4) | Block, ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
NEUT-2071CQ | Rabbit Anti-TNF Recombinant Antibody (clone 6E10) | Block, ELISA, IHC, WB | Rabbit IgG1 |
NEUT-2082CQ | Mouse Anti-TNF Recombinant Antibody (clone B-C7) | Block | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2092CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL923) | FC, IF, Neut, WB | Mouse IgG2b |
NEUT-2093CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL940) | FC, IP, Neut, WB | Mouse IgG1 |
NEUT-2094CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL956) | ELISA, Neut | Mouse IgG1, κ |
NEUT-2095CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL957) | ELISA, Neut, IHC | Mouse IgG1, κ |
NEUT-2096CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL959) | ELISA, ICC, Neut, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4460 | Rabbit Anti-TNF Recombinant Antibody (clone SI554DS) | ELISA | Rabbit IgG |
MOR-4462 | Rabbit Anti-TNF Recombinant Antibody (clone SI556DS) | FC | Rabbit IgG |
MOR-4463 | Rabbit Anti-TNF Recombinant Antibody (clone SI557DS) | FC | Rabbit IgG |
MOR-4464 | Rabbit Anti-TNF Recombinant Antibody (clone SI558DS) | FC | Rabbit IgG |
MOR-4465 | Rabbit Anti-TNF Recombinant Antibody (clone SI559DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0007-YC-S(P) | Human Anti-TNF Recombinant Antibody (clone cA2); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-0593-WJ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-0593-WJ-S(P)) | Neut, ELISA, RIA | Mouse scFv |
HPAB-0594-WJ-S(P) | Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-0594-WJ-S(P)) | ELISA | Humanized scFv |
HPAB-J0248-YC-S(P) | Human Anti-TNF Recombinant Antibody (clone F6); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-1564WJ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (clone 3B10) | ELISA, WB, Neut | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-169CQ | Goat Anti-TNF Polyclonal Antibody, Biotin | WB, ELISA(Det), ICC | Goat IgG |
MOB-170CQ | Mouse Anti-TNF Recombinant Antibody (clone YC146), Biotin | Neut, ELISA, ICC, FC | Mouse IgG1, κ |
HPAB-M0680-YC | Human Anti-TNF Recombinant Antibody (HPAB-M0680-YC) | ELISA, Neut, Inhib | Humanized IgG |
HPAB-M0681-YC | Human Anti-TNF Recombinant Antibody (HPAB-M0681-YC) | ELISA, Neut, Inhib | Humanized IgG |
HPAB-2679LY | Mouse Anti-TNF Recombinant Antibody (HPAB-2679LY) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0675-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0675-CN-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0676-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0676-CN-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0677-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0677-CN-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0678-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0678-CN-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0679-CN-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0679-CN-F(E)) | ELISA, Neut | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-768 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-006 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-010 | Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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